ISO/TR 12885:2008
Nanotechnologies — Health and safety practices in occupational settings relevant to nanotechnologies
ISO/TR 12885:2008 describes health and safety practices in occupational settings relevant to nanotechnologies.
ISO/TR 12885:2008 focuses on the occupational manufacture and use of engineered nanomaterials. It does not address health and safety issues or practices associated with nanomaterials generated by natural processes, hot processes and other standard operations which unintentionally generate nanomaterials, or potential consumer exposures or uses, though some of the information in ISO/TR 12885:2008 might be relevant to those areas.
Use of the information in ISO/TR 12885:2008 could help companies, researchers, workers and other people to prevent adverse health and safety consequences during the production, handling, use and disposal of manufactured nanomaterials. This advice is broadly applicable across a range of nanomaterials and applications.
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1. Introduction
2. Scope
Bibliography
3. Nanomaterials: description and manufacturing
3.1.1. Carbon containing nanomaterials
3.1.2. Oxides
3.1.3. Metals
3.1.4. Quantum dots
3.1.5. Organic polymeric nanomaterials
3.1.6. Bio-inspired nanomaterials
3.2.1. Typical production processes
3.2.2. Aerosol generation methods
3.2.3. Vapor deposition methods
3.2.4. Colloidal/self-assembly methods
3.2.5. Electrodeposition
3.2.6. Electro-spinning
3.2.7. Attrition methods
4. Hazard characterization
4.1.1. Basic principles and uncertainties
4.1.2. Potential relevance of health effects information abo
4.1.3. Relationship between toxicity and surface area, surfa
4.1.4. Inflammatory response to nanoparticles
4.1.5. Animal and cell-culture studies
4.1.5.1. Carbon containing nanomaterials
4.1.5.5. Organic polymeric nanomaterials
4.1.6. Observations from epidemiological studies involving f
4.2.1. Fire (exothermic events)
4.2.2. Safety considerations in manufacturing nanomaterials
5. Exposure assessment to nanomaterials
5.2.1. Routes of exposure
5.2.2. Metric for assessing exposure to airborne nanomateria
5.3.1. General
5.3.2. Mass concentration
5.3.3. Number concentration
5.3.3.2. Electrometers
5.3.4. Surface area concentration
5.3.5. Nanoparticle size distribution measurement
5.3.6. Sample collection for material characterization
5.3.7. Measurement of high length: width aspect ratio partic
5.3.8. Sampling strategy issues
5.4.1. Sampling
5.4.2. Sample characterization
6. Risk assessment in occupational settings
6.2.1. Quantitative and qualitative risk assessment
6.2.2. Hazard identification
6.2.3. Exposure-response assessment
6.2.4. Exposure assessment
6.2.5. Risk characterization
7. Control methodologies
7.2.1. Strategies for control
7.3.1. Exposure prevention
7.3.2. Control strategies
7.3.3. Eliminating the hazards through effective design
7.3.4. Substitution of raw materials, products, processes an
7.3.5. Engineering control techniques
Table 3 — Comparison of Biosafety Cabinet (BSC) Characterist
7.3.6. Administrative means for the control of workplace exp
7.3.7. Evaluating the work environment
7.3.8. Personal protective equipment (PPE)
Appendix 7.2. Advantages and disadvantages of different type
Annex A. Symbols and abbreviated terms
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1. Introduction
2. Scope
Bibliography
3. Nanomaterials: description and manufacturing
3.1.1. Carbon containing nanomaterials
3.1.2. Oxides
3.1.3. Metals
3.1.4. Quantum dots
3.1.5. Organic polymeric nanomaterials
3.1.6. Bio-inspired nanomaterials
3.2.1. Typical production processes
3.2.2. Aerosol generation methods
3.2.3. Vapor deposition methods
3.2.4. Colloidal/self-assembly methods
3.2.5. Electrodeposition
3.2.6. Electro-spinning
3.2.7. Attrition methods
4. Hazard characterization
4.1.1. Basic principles and uncertainties
4.1.2. Potential relevance of health effects information abo
4.1.3. Relationship between toxicity and surface area, surfa
4.1.4. Inflammatory response to nanoparticles
4.1.5. Animal and cell-culture studies
4.1.5.1. Carbon containing nanomaterials
4.1.5.5. Organic polymeric nanomaterials
4.1.6. Observations from epidemiological studies involving f
4.2.1. Fire (exothermic events)
4.2.2. Safety considerations in manufacturing nanomaterials
5. Exposure assessment to nanomaterials
5.2.1. Routes of exposure
5.2.2. Metric for assessing exposure to airborne nanomateria
5.3.1. General
5.3.2. Mass concentration
5.3.3. Number concentration
5.3.3.2. Electrometers
5.3.4. Surface area concentration
5.3.5. Nanoparticle size distribution measurement
5.3.6. Sample collection for material characterization
5.3.7. Measurement of high length: width aspect ratio partic
5.3.8. Sampling strategy issues
5.4.1. Sampling
5.4.2. Sample characterization
6. Risk assessment in occupational settings
6.2.1. Quantitative and qualitative risk assessment
6.2.2. Hazard identification
6.2.3. Exposure-response assessment
6.2.4. Exposure assessment
6.2.5. Risk characterization
7. Control methodologies
7.2.1. Strategies for control
7.3.1. Exposure prevention
7.3.2. Control strategies
7.3.3. Eliminating the hazards through effective design
7.3.4. Substitution of raw materials, products, processes an
7.3.5. Engineering control techniques
Table 3 — Comparison of Biosafety Cabinet (BSC) Characterist
7.3.6. Administrative means for the control of workplace exp
7.3.7. Evaluating the work environment
7.3.8. Personal protective equipment (PPE)
Appendix 7.2. Advantages and disadvantages of different type
Annex A. Symbols and abbreviated terms